Epidermal growth factor receptor inhibitor therapy for recurrent respiratory papillomatosis

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Epidermal growth factor receptor inhibitor therapy for recurrent respiratory papillomatosis

The epidermal growth factor pathway has been implicated in various tumors, including human papillomavirus (HPV) lesions such as recurrent respiratory papillomatosis (RRP). Due to the presence of epidermal growth factor receptors in RRP, epidermal growth factor receptor (EGFR) inhibitors have been utilized as adjuvant therapy. This case series examines the response to EGFR inhibitors in RRP. Fou...

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Therapy for recurrent respiratory papillomatosis.

Human papillomaviruses types 6 or 11 are aetiological agents of recurrent respiratory papillomatosis, a disease characterized by benign exophytic tumours usually on the vocal cords. Surgery debulks the tumours, but these growths generally recur at regular intervals. Adjunct medical treatments, aimed at containing the virus and growth of tumours, include indole-3-carbinol or its dimer diindolylm...

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ژورنال

عنوان ژورنال: F1000Research

سال: 2013

ISSN: 2046-1402

DOI: 10.12688/f1000research.2-202.v1